The Link to X-Ray Protein Crystallography


A. Crystal Production

(wet lab)

  1. Production
  2. Purification
  3. Crystallisation

 

>

B. Data Collection

(x-ray lab)

  1. Mounting
  2. Shooting
  3. Detection

>

C. Structure Solution

(computer lab)

  1. Indexing
  2. Integration
  3. Scaling
  4. Phasing
  5. Building
  6. Refinement
  7. Validation
  8. Publication

Trivia

Video of crystal growth
Animation of density fitting
History of Visualization of Biological Macromolecules (Martz & Francoeur)
Educational Resource of RCSB
Short explanation of protein crystallography on the Nobel website
Crystallography of transition states?
(PDB:1o08)
Video of a synchrotron (ionic liquid instead of protein)
Example for retracted structures (11) and related papers (10)
Nobelprizes in X-ray crystallography
- Nuclear magnetic resonance (NMR) - Electron microscopy and scanning tunneling microscopy


Mission / Organisations / Trivia / Links / Florian Fisch / 26 April 2011